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Holt Oram Syndrome associated with congenital panhypopituitarism rare association: A case report

Melissa G Al Beiruty, Lujain K AlFarran, Abdulmoein E Al-Agha

Holt Oram Syndrome (HOS) is a genetic condition characterized by varies skeletal and cardiac anomalies. However, HOS associated with panhypopiuitarism has never been reported. Thus, we reported a case of a 25 days old male neonate with bilateral absent radius, short curved ulnar, absent thumbs and micropenis associated with recurrent episode of persistent hypoglycemia, due to hypopituitarism.

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