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Human lens epithelium structural and functional studies in association with cataract formation

Sofija Andjelic* , Marko Hawlina

This review summarizes recent work related to the structure and the function of the human anterior lens epithelium and its role in the formation of cataract, one of the central issues in eye research. It emphasizes that the human lens capsule preparation isolated during the cataract surgery is an adequate source for the studies of lens epithelial cells and it highlights the possibilities for studying the changes in intracellular calcium homeostasis, macromolecular components and structure of lens epithelium associated with cataract.