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Intake of Dietary Fiber as a putative prevention of Colorectal Cancer in Pakistan

Laila Tul Qadar, Faryal Tahir, Syeda Zubaria Qamar, Sayed Mustafa Mahmood Shah

Colorectal cancer (CRC) is an unchecked proliferation of abnormal cells that initiates in the colon or rectum. Most of them start as small growths termed adenomatous polyps causing alteration in the layers of colon, spreading to nearby lymph nodes and distant parts of the body. Its incidence is increasingly reported in younger population i.e. less than 40 years of age. In Pakistan, it is concerned that an aging population over the coming decade and changing lifestyle patterns may lead to a higher incidence of CRC [1]. Risk factors of colorectal carcinoma are enumerated as older age, inherited gene mutations, inflammatory intestinal conditions, diabetes, smoking, alcohol intake, low fiber and high fat diet and sedentary life style [2]. Bleeding per rectum and anaemia are high risk clinical features for CRC.