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Survival analysis and postoperative complications after ventricular assist device implantation; prognostic value of INTERMACS scale

Ahmed R. Ahmed, Pizanis Nikolaus, Koch Achim, Carstens Henning, Rassaf Tienush, Ludike Peter, Kamler Markus*

Background: Ventricular assist devices (VADs) improve survival and quality of life in patients with refractory heart failure. This study retrospectively evaluates patients’ profiles, clinical outcome in patients who underwent LVAD implantation in regard to their INTERMACS level.

Methods: In a single center analysis, data of 104 patients after LVAD implantation between August 2010 and March 2015 were analyzed retrospectively. According to INTERMACS level, 3 groups were compared: Group A (INTERMCAS level 1, n=27 patients), group B (INTERMACS level 2/3, n=47) and group C (INTERMACS level 4-6, n=30). Preoperative parameters and postoperative outcome were compared between groups.

Results: Mortality was higher in group A compared to group B (p=0.017) and group C (p=0.017). Sepsis was the most common post-operative complication after LVAD implantation.

Conclusion: INTERMACS level was related to outcome after LVAD implantation. Optimization of preoperative volume status, preload and sepsis management are recommended to lower mortality in these patients.