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Pathophysiology and management of diabetic foot ulcer: Review.

Kedar Prasad Meena*, Tripty Karri, Pradeep Samal, Divya Jaiswal, Sandeep Yadav

Diabetes is a common disease affected by many people throughout the world. The many tissues and organs are affected by long term hyperglycemia. It is optimized by different management approaches and sometimes along with adjuvant therapy. Based on studies advanced dressing, blood sugar control wound debridement and offloading modalities should always be a part of diabetic foot ulcer management. If this is not well controlled by antidiabetic medications, it will in chronic complications including heart disease, stroke, diabetic nephropathy, neuropathy, retinopathy, peripheral arterial disease and diabetic foot with poor wound healing. Diabetic Foot Ulcer (DFU) is one of the costly and devasting long term aggravation of diabetes mellitus, which affects around 15%-20% of diabetic patients during their lifetime. Chronic foot ulcer heals slowly or sometimes not at all. It might show long term hospitalization. The cost of medical care products associated with ulcer healing results in a burden on the healthcare system and variability in etiology observed in foot ulcers. The management of diabetic foot ulcer is a multidisciplinary approach for the management of wound.